Author

T. Ksiazek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Pathology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

B. Gong· 4 shared Q. Chang· 4 shared Y. Liu· 3 shared Z. Su· 3 shared A. Bukreyev· 2 shared A. Drelich· 2 shared A. Gaitas· 2 shared C. Zhou· 2 shared

Activity by Year

2017-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersPathology

B. Gong

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell-type apoptosis in lung during SARS-CoV-2 infection

Y. Liu, T. M. Garron, Q. Chang, Z. Su, C. Zhou, E. C. Gong, J. Zheng, W. Yin, T. Ksiazek, T. Brasel, Y. Jin, P. Boor, J. E. Comer, B. Gong

This study investigates cell-type apoptosis in lung tissues during SARS-CoV-2 infection, finding both intrinsic and extrinsic apoptotic pathways are activated, while some cell types remain refractory to infection.

bioRxiv · Dec 23, 2020Pathology

EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammation

J. Xiao, B. Zhang, Z. Su, Y. Liu, T. R. Shelite, Q. Chang, P. Wang, A. Bukreyev, L. Soong, Y. Jin, T. Ksiazek, A. Gaitas, S. L. Rossi, J. Zhou, M. Laposata, , B. Gong

This study shows EPAC1 regulates vWF secretion from endothelial cells during inflammation via the PI3K/eNOS pathway, with implications for thrombosis control.

bioRxiv · Sep 4, 2020 · PreprintCell Biology

Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient

J. Harcourt, A. Tamin, X. Lu, S. Kamili, S. Kumar Sakthivel, L. Wang, J. Murray, K. Queen, B. Lynch, B. Whitaker, Y. Tao, C. Paden, J. Zhang, Y. Li, A. Uehara, , N. J. Thornburg

The paper isolates and characterizes SARS-CoV-2 from the first US COVID-19 patient, showing high replication in Vero cells and depositing the strain for public use.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections

Z. Su, Q. Chang, A. Drelich, T. Shelite, B. Judy, Y. Liu, J. Xiao, C. Zhou, X. He, T. Saito, S. Tang, L. Soong, M. Wakamiya, X. Fang, A. Bukreyev, , B. Gong

This study shows that ANXA2 depletion increases CMHs in rickettsia and Ebola virus infections by disrupting BBB tight junctions.

bioRxiv · Dec 2, 2019Pathology

Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

X. He, A. Drelich, Q. Chang, D. Gong, Y. Zhou, Y. Qu, S. Yu, Y. Yang, J. Qian, Y. Qiu, S.-J. Tang, A. Gaitas, T. Ksiazek, Z. Xu, M. Wakamiya, , B. Gong

This study shows that EPAC1 promotes ANXA2 translocation to endothelial cell surfaces, enhancing plasminogen to plasmin conversion and fibrinolysis.

bioRxiv · Oct 1, 2017Cell Biology