Author

S.-Y. Hwang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

A. Baum· 1 shared A. Garcia-Sastre· 1 shared G. Yoon· 1 shared H. Jo· 1 shared H. Jung· 1 shared H. Woo· 1 shared H. Y. Seo· 1 shared H.-G. Jung· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiophysics

A. Baum

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction

S.-Y. Hwang, K.-H. Jeon, H.-J. Lee, I. Moon, S. Jung, S.-A. Kim, H. Jo, S. Park, M. Ahn, S.-Y. Kwak, Y. Na, Y. Kwon

This study synthesizes and evaluates chalcone and pyrazoline derivatives as ELF3-MED23 PPI inhibitors, showing compound 10 effectively reduces HER2 levels and induces apoptosis in HER2-positive gastric cancer cells.

bioRxiv · Mar 1, 2024Pharmacology & Toxicology

Enhanced Omicron subvariant cross-neutralization efficacy of a monovalent SARS-CoV-2 BA.4/5 mRNA vaccine encoding a noncleaved, nonfusogenic spike antigen

H. Y. Seo, H. Jung, H. Woo, H.-G. Jung, Y. Bak, S.-Y. Lee, Y.-M. Son, G. Yoon, Y.-M. Son, S.-Y. Hwang, I. Park, J.-S. Shin, J.-W. Oh

This study develops a modified SARS-CoV-2 spike antigen that enhances cross-neutralization against Omicron subvariants, despite reduced neutralizing potency.

bioRxiv · Sep 10, 2023 · PreprintImmunology

Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression

S. Doganay, M. Y. Lee, A. Baum, J. Peh, S.-Y. Hwang, J.-Y. Yoo, P. J. Hergenrother, A. Garcia-Sastre, S. Myong, T. Ha

The paper identifies early antiviral gene expression patterns and shows that RLRs drive stochastic IFNB1 expression independent of IFN.

bioRxiv · Aug 31, 2017Biophysics