Cell BiologybioRxivPreprint
A Drosophila model for Dent disease reveals impaired ER export of Cubilin as pathogenic mechanism
Salómon Christer, Zvonimir Marelja, Hannah Hauschild…·Matias Simons
This paper establishes a Drosophila model for Dent disease, showing that ClC-c depletion causes Cubilin ER retention and secretory pathway defects, revealing a new pathogenic mechanism.
DOI 10.1101/2025.03.05.641445