Author

Sally A. V. Draycott

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Adam J. MeadiD· 1 shared Christina Simoglou KaraliiD· 1 shared Christopher A. O’CallaghaniD· 1 shared David R. GreavesiD· 1 shared Eileen McNeilliD· 1 shared Gareth S. D. PurvisiD· 1 shared Gillian DouglasiD· 1 shared Jiahao JiangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam J. MeadORCID

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1 paper

Recent·Most cited

Hypercholesterolaemia promotes epigenetic memory in hematopoietic stem cells that persists after lipid lowering and causes systemic immunometabolic dysfunction mediated by macrophage metabolic reprogramming

Gareth S. D. Purvis, Jiahao Jiang, Thomas K. Hiron, Christina Simoglou Karali, Matthew D. Baxter, Rong Li, Rohit Vijjhalwar, Marina Diotallevi, Sally A. V. Draycott, Surawee Chuaiphichai, Gillian Douglas, Eileen McNeill, Adam J. Mead, David R. Greaves, Christopher A. O’Callaghan, Keith M. Channon

This study shows that high cholesterol induces epigenetic changes in hematopoietic stem cells that persist after cholesterol reduction, leading to systemic immunometabolic dysfunction.

bioRxiv · Sep 15, 2025 · PreprintImmunology