The Balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells
Róbert Zach, Michael Annis, Sandra M. Martin-Guerrero, Abdulrahman Alatawi, Kim Hou Chia, Megan Meredith, Kay Osborn, Nisha Peter, William Pearce, Jessica Booth, Mohan B. Rajasekaran, Samantha Dias, Lily Coleman-Evans, William R. Foster, Jon Alexander Harper, , Helfrid Hochegger
This study shows that the balance between B55α and Greatwall expression levels determines cancer cell sensitivity to Greatwall inhibition.
Nature Communications · Aug 27, 2025Peer-reviewedCell Biology