Identification of a novel false-positive mechanism in RapidFire mass spectrometry and application in drug discovery
De Lin, Lesley-Anne Pearson, Shamshad Ahmad, Sandra O’Neill, John M. Post, Colin Robinson, Duncan E. Scott, Ian Hugh Gilbert
The paper identifies a novel false-positive mechanism in RapidFire mass spectrometry and develops a pipeline to detect and mitigate these false positives in drug discovery.
bioRxiv · Jan 24, 2025 · PreprintBiochemistry