The toll-like receptor 7 agonist imiquimod increases ethanol self-administration and induces expression of toll-like receptor related genes
Dennis F. Lovelock, Wen Liu, Sarah E. Langston, Jiaqi Liu, Kalynn J. Van Voorhies, Kaitlin A. Giffin, Ryan P. Vetreno, Fulton T. Crews, Joyce Besheer
This study shows that TLR7 activation with imiquimod increases ethanol self-administration and induces TLR-related gene expression in rats, with sex-specific effects on drinking behavior and molecular responses.
Addiction Biology · Apr 22, 2022Peer-reviewedNeuroscience