Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress
Lewis R Depaauw-Holt, Manon Duquenne, Sarah Hamane, Sarah Peyrard, Benjamin Rogers, Clara Ireland, Yusuke Nasu, Stephanie E. Fulton, Anthony Bosson, Thierry Alquier, Ciaran Murphy‐Royal
The paper investigates how stress affects activity levels through interactions between orexin neurons and astrocytes, finding that astrocytic glucocorticoid receptors mediate sex-specific changes in neuronal firing and activity.
Nature Communications · Jul 10, 2025Peer-reviewedNeuroscience