Author

Sayran Saber

University of Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Charles F. BaeriD· 3 shared Moein RajaeiiD· 3 shared Erik C. AnderseniD· 2 shared Juannan ZhouiD· 2 shared Robyn E. TannyiD· 2 shared Amber J. Singh· 1 shared Ayush S. SaxenaiD· 1 shared Ayush SaxenaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersEvolutionary Biology

Charles F. BaerORCID

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Author profile →

4 papers

Recent·Most cited

Evolution of the rate, spectrum, and fitness effects of mutation under minimal selection in Caenorhabditis elegans

Sayran Saber, Md. Monjurul Islam Rifat, Fahimeh Rahimi, Michael C. Snyder, Amber J. Singh, Benjamin Eickwort, Yell Newhall, Moein Rajaei, Ayush Saxena, Robyn E. Tanny, Vaishali Katju, Erik C. Andersen, Juannan Zhou, Charles F. Baer

This study tracks mutation rates and fitness effects in C. elegans under minimal selection, finding increased indel mutation rates and no change in nucleotide substitution rates.

Genetics · Mar 26, 2026Peer-reviewedEvolutionary Biology

Strain-specific structural variant landscapes shape mutation retention following mutagenesis in Caenorhabditis elegans

Rohit Kapila, Sayran Saber, R.K. Verma, G. Blanco, Victoria K. Eggers, Janna L. Fierst

The paper examines mutation retention in C. elegans strains after mutagenesis, finding strain-specific differences in structural variant accumulation and mutation retention.

bioRxiv · Apr 16, 2025 · PreprintBioinformatics

Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

Timothy A. Crombie, Moein Rajaei, Ayush S. Saxena, Lindsay Johnson, Sayran Saber, Robyn E. Tanny, José Miguel Ponciano, Erik C. Andersen, Juannan Zhou, Charles F. Baer

This study infers the distribution of fitness effects of mutations in C. elegans using recombinant inbred lines, finding that positive effects are common but LD can skew results.

Genetics · Aug 14, 2024Peer-reviewedEvolutionary Biology

Mutation, selection, and the prevalence of the C. elegans mortal germline phenotype

Sayran Saber, Michael Snyder, Moein Rajaei, Charles F. Baer

The paper quantifies mutation rates and selection pressures for the Mrt phenotype in C. elegans, suggesting balancing selection maintains weak Mrt variants.

G3 Genes Genomes Genetics · Mar 21, 2022Peer-reviewedGenetics