Ayush S. Saxena

The paper estimates the mutation rate and removal efficiency of structural variants in C. elegans using long-read sequencing and finds a lower mutation rate compared to SNVs and short indels, with natural selection effectively removing SVs in both exonic and intergenic regions.

This study infers the distribution of fitness effects of mutations in C. elegans using recombinant inbred lines, finding that positive effects are common but LD can skew results.