Author

Scott Rata

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Leonid PeshkiniD· 2 shared Marc W. KirschneriD· 2 shared Alexander LukyanoviD· 1 shared Andrew AngeliD· 1 shared Craig J. ThomasiD· 1 shared Emily SewardiD· 1 shared Françoise S. HoweiD· 1 shared Jane MelloriD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersSystems Biology

Leonid PeshkinORCID

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3 papers

Recent·Most cited

Identification of Kinases Activated by Multiple Pro-Angiogenic Growth Factors

Scott Gruver, Scott Rata, Leonid Peshkin, Marc W. Kirschner

The paper identifies kinases critical for endothelial cell proliferation across multiple pro-angiogenic growth factors using a quantitative assay and kinome regression.

Frontiers in Pharmacology · Jan 4, 2023Peer-reviewedSystems Biology

An optimal set of inhibitors for Reverse Engineering via Kinase Regularization.

Scott Rata, Jonathan Scott Gruver, Natalia Trikoz, Alexander Lukyanov, Janelle S. Vultaggio, Michele Ceribelli, Craig J. Thomas, Taranjit S. Gujral, Marc W. Kirschner, Leonid Peshkin

The paper presents a dataset of kinase inhibitor profiles and introduces an improved method to identify key kinases involved in cellular phenotypes using quantitative assays and machine learning.

bioRxiv · Sep 26, 2020 · PreprintSystems Biology

Antisense transcription-dependent chromatin signature modulates sense transcription and transcript dynamics

Tom Brown, Françoise S. Howe, Struan C. Murray, Meredith Wouters, Philipp Lorenz, Emily Seward, Scott Rata, Andrew Angel, Jane Mellor

The paper shows antisense transcription affects sense transcript dynamics through a chromatin signature, with effects observed in yeast and human genes.

Molecular Systems Biology · Feb 1, 2018Peer-reviewedSystems Biology