Author

Struan C. Murray

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Assay:ChIP-seq· 2 Organism:human· 2 Organism:yeast· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrew AngeliD· 4 shared Jane MelloriD· 4 shared Meredith WoutersiD· 3 shared Shidong Xi· 3 shared Tom BrowniD· 3 shared Charlotte L. GeorgeiD· 2 shared Françoise S. HoweiD· 2 shared Harry FischliD· 2 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersMolecular Biology

Andrew AngelORCID

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4 papers

Recent·Most cited

Single Nucleotide Resolution 4sU Sequencing (SNU-Seq) reveals the transcriptional responsiveness of an epigenetically primed human genome

Umut Gerlevik, Philipp Lorenz, Anna R Lamstaes, Harry Fischl, Shidong Xi, Aksel J. Saukko‐Paavola, Struan C. Murray, Tom Brown, Alexander Welch, Charlotte L. George, Andrew Angel, André Furger, Jane Mellor

This paper introduces SNU-Seq and sf4sU-Seq methods to map nascent transcripts at single-nucleotide resolution, revealing transcriptional responsiveness in an epigenetically primed human genome.

bioRxiv · Jul 14, 2021 · PreprintMolecular Biology

Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels

Jack Feltham, Shidong Xi, Struan C. Murray, Meredith Wouters, Julian Urdiain‐Arraiza, Raphael Heilig, Charlotte L. George, Anna F. Townley, Emile Roberts, Benedikt Mathias Kessler, Sabrina Liberatori, Philip D. Charles, Andrew Angel, Román Fischer, Jane Mellor

The paper shows that transcriptional changes during biological rhythms do not directly affect protein levels, which remain constant due to slow turnover rates and post-translational regulation.

bioRxiv · Jun 10, 2020 · PreprintMolecular Biology

H3K4me3 is neither instructive for, nor informed by, transcription.

Struan C. Murray, Philipp Lorenz, Françoise S. Howe, Meredith Wouters, Tom Brown, Shidong Xi, Harry Fischl, Walaa Khushaim, Joseph Regish Rayappu, Andrew Angel, Jane Mellor

The paper investigates the relationship between H3K4me3 and transcription, finding no direct instructive or informative link between the two on a genome-wide scale in budding yeast.

bioRxiv · Jul 19, 2019 · PreprintGenomics

Antisense transcription-dependent chromatin signature modulates sense transcription and transcript dynamics

Tom Brown, Françoise S. Howe, Struan C. Murray, Meredith Wouters, Philipp Lorenz, Emily Seward, Scott Rata, Andrew Angel, Jane Mellor

The paper shows antisense transcription affects sense transcript dynamics through a chromatin signature, with effects observed in yeast and human genes.

Molecular Systems Biology · Feb 1, 2018Peer-reviewedSystems Biology