Author

Sean M. Thomas

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew J. OliveiD· 2 shared Joshua J. ObariD· 2 shared Abigail P. McGeeiD· 1 shared Agustin Reséndiz-SharpeiD· 1 shared Alayna K. Caffrey-Carr· 1 shared Alexander W Rapp· 1 shared Alexander W. RappiD· 1 shared Brandon S. RossiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Andrew J. OliveORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Trans-Kingdom dsRNA Sensing: Aspergillus fumigatus Mycovirus Activates MDA5/MAVS Immunity and Limits Allergic Bronchopulmonary Aspergillosis

Alexander W. Rapp, Xi Wang, Brandon S. Ross, Alayna K. Caffrey-Carr, Sean M. Thomas, Agustin Reséndiz-Sharpe, Andrew J. Olive, Katrien Lagrou, Robert A. Cramer, Joshua J. Obar

The paper shows that dsRNA mycoviruses in Aspergillus fumigatus enhance MDA5/MAVS signaling and reduce virulence in chronic allergic aspergillosis.

bioRxiv · May 18, 2026 · PreprintImmunology

TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation

Sean M. Thomas, Abigail P. McGee, Taryn E Vielma, Laurisa M Ankley, Alexander W Rapp, Kayla N. Conner, Francois LeSage, Christopher Tanner, Eleanor C. Scheeres, Joshua J. Obar, Andrew J. Olive

This study shows TGFβ primes alveolar-like macrophages to induce type I IFN responses upon TLR2 activation through mitochondrial ROS and IRF3/7.

The Journal of Immunology · May 1, 2026Peer-reviewedImmunology