Robert A. Cramer

The paper identifies a strain-specific metabolic role for Uge3 in H-MORPH A. fumigatus strains, linking it to virulence and central carbon metabolism.

This study identifies IngB as an epigenetic regulator of azole tolerance in Aspergillus fumigatus, showing that its loss enables rapid acquired resistance under azole stress.

The paper shows that dsRNA mycoviruses in Aspergillus fumigatus enhance MDA5/MAVS signaling and reduce virulence in chronic allergic aspergillosis.

This study identifies arvA as critical for Aspergillus fumigatus morphogenesis and antifungal drug susceptibility but shows it is not required for virulence in murine models.

This study identifies iron overload and metabolic reprogramming in myeloid cells as drivers of susceptibility to Aspergillus fumigatus in influenza-associated pulmonary aspergillosis.

This study identifies a novel antifungal compound targeting ALS, validated through genome mining, biochemical assays, and a mouse model of invasive aspergillosis.

This study identifies a ceramide synthase, barA, as important for biofilm morphology and antifungal drug resistance in Aspergillus fumigatus.

This study uses transcriptomics to identify metabolic shifts and genes important for maintaining mature A. fumigatus biofilms.

This study identifies giant transposons called Starships in Aspergillus fumigatus that generate genomic and phenotypic heterogeneity across strains.

CF-Seq provides a web tool for re-analyzing CF pathogen RNA-seq data, enabling efficient filtering, visualization, and hypothesis generation across multiple studies.

This study combines pan-, population-, and phylo-genomic analyses of Aspergillus fumigatus to reveal population structure, lineage-specific diversity, and ecological drivers of virulence.