Trans-Kingdom dsRNA Sensing: Aspergillus fumigatus Mycovirus Activates MDA5/MAVS Immunity and Limits Allergic Bronchopulmonary Aspergillosis
Alexander W. Rapp, Xi Wang, Brandon S. Ross…·Joshua J. Obar
The paper shows that dsRNA mycoviruses in Aspergillus fumigatus enhance MDA5/MAVS signaling and reduce virulence in chronic allergic aspergillosis.