Totum-448, a polyphenol-rich plant extract, decreases hepatic steatosis and inflammation in diet-induced MASLD mice
Joost M. Lambooij, Vivien Chavanelle, Marie Vallier, Hendrik J.P. van der Zande, Yolanda F. Otero, Frank Otto, Robbie Schuurman, Florian Le Joubioux, Thierry Maugard, Martin A. Giera, Sebastien L. Peltier, Arnaud Zaldumbide, Pascal Sirvent, Bruno Guigas
Totum-448 reduces hepatic steatosis and inflammation in diet-induced MASLD mice without affecting body weight or microbiota.
npj gut and liver. · Sep 3, 2025Peer-reviewedPhysiology