Prior epigenetic status predicts future susceptibility to seizures in mice
Benjamin D. Boros, Mariam Alexandra Gachechiladze, Juanru Guo, Dylan A. Galloway, Shayna M. Mueller, Mark Shabsovich, Allen Yen, Alexander J. Cammack, Tao Shen, Robi David Mitra, Joseph D. Dougherty, Jonathan S. Mill
The paper shows that epigenetic variation recorded in mice during development predicts seizure susceptibility, with specific loci linked to human epilepsy genes.
bioRxiv · Mar 20, 2025 · PreprintGenomics