Author

Mark Shabsovich

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexander J. CammackiD· 2 shared Dylan A. Galloway· 2 shared Jonathan S. MilliD· 2 shared Joseph D. DoughertyiD· 2 shared Robi David MitraiD· 2 shared Allen YeniD· 1 shared Arnav MoudgiliD· 1 shared Benjamin D. BorosiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Alexander J. CammackORCID

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3 papers

Recent·Most cited

miR-146a is a Pleiotropic Regulator of Motor Neuron Degeneration

Dylan A. Galloway, Hunter L. Patterson, Mariah L. Hoye, Tao Shen, Mark Shabsovich, Kathleen M. Schoch, Cindy V. Ly, Jonathan S. Mill

The paper shows miR-146a regulates multiple aspects of motor neuron degeneration in ALS, with genetic deletion extending survival and causing age-related paralysis and inflammation.

Proceedings of the National Academy of Sciences · Jun 1, 2026Peer-reviewedNeuroscience

Prior epigenetic status predicts future susceptibility to seizures in mice

Benjamin D. Boros, Mariam Alexandra Gachechiladze, Juanru Guo, Dylan A. Galloway, Shayna M. Mueller, Mark Shabsovich, Allen Yen, Alexander J. Cammack, Tao Shen, Robi David Mitra, Joseph D. Dougherty, Jonathan S. Mill

The paper shows that epigenetic variation recorded in mice during development predicts seizure susceptibility, with specific loci linked to human epilepsy genes.

bioRxiv · Mar 20, 2025 · PreprintGenomics

A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues

Alexander J. Cammack, Arnav Moudgil, Tomás Lagunas, Michael J. Vasek, Mark Shabsovich, June He, Xuhua Chen, Michael Wilkinson, Timothy M. Miller, Robi David Mitra, Joseph D. Dougherty

The paper introduces FLEX Calling Cards, a method to map transcription factor-DNA interactions in specific cell types within heterogeneous tissues using viral delivery and transposon insertion.

bioRxiv · Oct 17, 2019 · PreprintNeuroscience