Author

Shen Yan

University Children's Hospital Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Bernard CirauloiD· 2 shared Marc Thomas Schönholzer· 2 shared Martin BaumgartneriD· 2 shared Amin AllalouiD· 1 shared Ana Guerreiro StückliniD· 1 shared Andrea Joseph De MicheliiD· 1 shared Andreas Postlmayr· 1 shared Astrid Sanchez Bergman· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Bernard CirauloORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MAP4K inhibition by the CNS penetrant inhibitor famlasertib restrains medulloblastoma dissemination without developmental toxicity

Marc Thomas Schönholzer, Meng-Syuan Lin, Shen Yan, Veronica Akle Alvarez, Amin Allalou, Bernard Ciraulo, Dejana Versamento, Levi Luca Kopp, Dina Hochuli, Bleiker Tanja, Welti Annik, Stephan C. F. Neuhauss, Martin Baumgartner

This study shows that famlasertib, a MAP4K inhibitor, reduces medulloblastoma cell invasion in vitro and in zebrafish models without causing developmental toxicity.

bioRxiv · Jul 23, 2026 · PreprintCancer Biology

Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation

Andreas Postlmayr, Astrid Sanchez Bergman, Jacob Torrejon-Diaz, Bernard Ciraulo, Shen Yan, Nina Hofmann, Samanta Kisele, Rosalie Dobler, Charbel Machaalani, Marc Thomas Schönholzer, Laura Priego-González, Andrea Joseph De Micheli, Ernesto Berenjeno‐Correa, Luca Baroncini, Michael Andreas Grotzer, , Ana Guerreiro Stücklin

The paper identifies functionally distinct ALK and ROS1 fusions in infant-type hemispheric gliomas, showing they converge on STAT3 and SHP2 activation through different mechanisms.

Cell Reports · Mar 1, 2026Peer-reviewedCancer Biology