Martin Baumgartner

Quantitative live imaging reveals region-dependent medulloblastoma disseminationin the zebrafish brain

This study uses live imaging in zebrafish to show that hindbrain medulloblastoma cells spread more frequently than forebrain or midbrain tumors and that dasatinib reduces dissemination.

MAP4K inhibition by the CNS penetrant inhibitor famlasertib restrains medulloblastoma dissemination without developmental toxicity

This study shows that famlasertib, a MAP4K inhibitor, reduces medulloblastoma cell invasion in vitro and in zebrafish models without causing developmental toxicity.

Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion

This study maps the FRS2 interactome in medulloblastoma cells, identifying novel proteins involved in cell migration and invasion, and highlights FRS2's role in tumor aggressiveness.

Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation

The paper identifies functionally distinct ALK and ROS1 fusions in infant-type hemispheric gliomas, showing they converge on STAT3 and SHP2 activation through different mechanisms.

PHIROS: An integrated microfluidic platform for multi-day high-resolution imaging of organotypic slices

PHIROS enables long-term, high-resolution imaging of organotypic brain slices with controlled perfusion, revealing dynamic tumor-astrocyte interactions and mitochondrial transfer.