Immune activation during broadly neutralizing antibody-mediated HIV suppression prior to post-intervention control
Julia A. Wagner, Demi A. Sandel, Ravi K. Patel, George W. Gruenhagen, Rafael Tibúrcio, Shalyeen S. Singh, Kaiti Schwartz, Michela Traglia, Pamela Milani, Clara Di Germanio, Shlomi Ilan, Thomas Dalhuisen, Rebecca Hoh, Meghann C. Williams, Michiko Shimoda, , Rachel Lena Rutishauser
This study shows that bNAb-mediated HIV suppression is linked to increased immune activation compared to ART suppression, with unique transcriptional patterns in controllers.
bioRxiv · Jun 2, 2026 · PreprintImmunology