Author

Shu Tu

Creighton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Bechara KachariD· 2 shared Celia R. Bloom· 2 shared David Z. Z. HeiD· 2 shared Huizhan LiuiD· 2 shared Jian ZuoiD· 2 shared Litao TaoiD· 2 shared Samadhi KulasooriyaiD· 2 shared Sarath VijayakumariD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Bechara KacharORCID

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3 papers

Recent·Most cited

The Dual Molecular Identity of Vestibular Kinocilia: Bridging Structural and Functional Traits of Primary and Motile Cilia

Zhenhang Xu, Amirrasoul Tavakoli, Samadhi Kulasooriya, Huizhan Liu, Shu Tu, Celia R. Bloom, Yi Li, Tirone D Johnson, Jian Zuo, Litao Tao, Bechara Kachar, David Z. Z. He

The paper identifies the kinocilium as a unique organelle with molecular features of both primary and motile cilia, showing it generates force in the hair bundle.

bioRxiv · Apr 16, 2025 · PreprintNeuroscience

Hair Bundle Degeneration is a Key Contributor to Age-Related Vestibular Dysfunction

Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia R. Bloom, Shu Tu, Benjamin J. Borgmeier, Mi Ζhou, Litao Tao, Bechara Kachar, David Z. Z. He

The paper identifies age-related molecular and cellular changes in vestibular hair cells that contribute to vestibular dysfunction by impairing mechanotransduction and hair bundle integrity.

bioRxiv · Feb 2, 2025 · PreprintNeuroscience

In Silico Transcriptome-based Screens Identify Epidermal Growth Factor Receptor Inhibitors as Therapeutics for Noise-induced Hearing Loss

Sarath Vijayakumar, Joseph DiGuiseppi, Parinaz J. Dabestani, William G. Ryan, René Vielman Quevedo, Yuju Li, Jack Diers, Shu Tu, Jonathan P. Fleegel, Cassidy Nguyen, Lauren M. Rhoda, Ali Sajid Imami, Abdul-Rizaq Ali Hamoud, Sándor Lovas, Robert Erne McCullumsmith, , Jian Zuo

This paper identifies EGFR inhibitors as potential therapeutics for noise-induced hearing loss using in silico transcriptome-based drug screening and experimental validation in zebrafish and mouse models.

Science Advances · Jun 19, 2024Peer-reviewedNeuroscience