Author

Yuju Li

Creighton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jian ZuoiD· 3 shared Marisa ZallocchiiD· 2 shared Sarath VijayakumariD· 2 shared Abdul-Rizaq Ali HamoudiD· 1 shared Ali Sajid ImamiiD· 1 shared Andrei N. Lukashin· 1 shared Cassidy Nguyen· 1 shared Ian John RusselliD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Jian ZuoORCID

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3 papers

Recent·Most cited

In Silico Transcriptome-based Screens Identify Epidermal Growth Factor Receptor Inhibitors as Therapeutics for Noise-induced Hearing Loss

Sarath Vijayakumar, Joseph DiGuiseppi, Parinaz J. Dabestani, William G. Ryan, René Vielman Quevedo, Yuju Li, Jack Diers, Shu Tu, Jonathan P. Fleegel, Cassidy Nguyen, Lauren M. Rhoda, Ali Sajid Imami, Abdul-Rizaq Ali Hamoud, Sándor Lovas, Robert Erne McCullumsmith, , Jian Zuo

This paper identifies EGFR inhibitors as potential therapeutics for noise-induced hearing loss using in silico transcriptome-based drug screening and experimental validation in zebrafish and mouse models.

Science Advances · Jun 19, 2024Peer-reviewedNeuroscience

Optogenetics reveals roles for supporting cells in force transmission to and from outer hair cells in the mouse cochlea

Victoria A. Lukashkina, Snezana Levic, Patrício M. V. Simões, Zhenhang Xu, Yuju Li, Trevor Haugen, Jian Zuo, Andrei N. Lukashin, Ian John Russell

The paper uses optogenetics to study the role of supporting cells in force transmission to and from outer hair cells in the mouse cochlea, finding that hyperpolarizing these cells suppresses cochlear amplification and alters mechanical responses.

Journal of Neuroscience · Dec 1, 2023Peer-reviewedNeuroscience

In silico transcriptomics identifies FDA-approved drugs and biological pathways for protection against cisplatin-induced hearing loss

Pezhman Salehi, Marisa Zallocchi, Sarath Vijayakumar, Madeleine E. Urbanek, Kimberlee P. Giffen, Yuju Li, Santanu Hati, Jian Zuo

The paper uses in silico transcriptomics to identify FDA-approved drugs and pathways that protect against cisplatin-induced hearing loss, validating niclosamide as a potential otoprotectant.

bioRxiv · Jan 26, 2022 · PreprintNeuroscience