Author

Shuyi Liu

Wenzhou Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Shengzhou WuiD· 2 shared Baoxing Dong· 1 shared Bingbing ReniD· 1 shared Chenxiang XiiD· 1 shared Dandan BaiiD· 1 shared Ge ShaniD· 1 shared Haiyan JiangiD· 1 shared Hong WangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Shengzhou WuORCID

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3 papers

Recent·Most cited

Apolipoprotein E4 Exacerbates Aβ Oligomer-Induced Synaptotoxicity through Promoting Autophagic Degradation of Glutathione Peroxidase 4

Jing Zhou, Hongji Liao, Wenjing Liang, Shuyi Liu, Jingjing Cai, Yu Liu, Yimei Liu, Zhonglou Zhou, Shengzhou Wu

This study shows APOE4 worsens Aβ oligomer-induced synaptotoxicity by promoting autophagic degradation of STIM1 and Gpx4, leading to mitochondrial dysfunction and synaptic loss.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

Modeling Post-Gastrula Development via Bidirectional Pluripotent Stem Cells

Kuisheng Liu, Zihui Yan, Dandan Bai, Rui Jiang, Yan Bi, Xiangjun Ma, Jiani Xiang, Yifan Sheng, Baoxing Dong, Zhiyuan Ning, Shanru Yi, Yingdong Liu, Xinyi Lei, Yanping Jia, Yan Zhang, , Wenqiang Liu

This study develops bidirectional pluripotent stem cells (BPSCs) capable of generating both trophoblast and epiblast lineages, enabling the recapitulation of post-gastrula development in vitro and in vivo.

Cell Research · Aug 29, 2025Peer-reviewedDevelopmental Biology

Inhibition of serine racemase prevents diabetic retinopathy

Haiyan Jiang, Piansi Zhou, Xue Jiang, Xiong Wu, Yandie Mao, Shuyi Liu, Shiqi Tang, Jing Zhou, Zhiwen Zhang, Bingbing Ren, Ge Shan, Jia Qu, Shengzhou Wu

This study shows that inhibiting serine racemase with L-ABH prevents diabetic retinopathy by protecting retinal cells and maintaining glucose homeostasis in diabetic mice.

bioRxiv · Jun 30, 2024 · PreprintBiochemistry