Ge Shan

The paper shows that spatial clustering of piRNA genes in nematodes enhances transcription through phase separation involving UAD-2 and the SUMO regulatory factors GEI-17 and TOFU-3.

The paper identifies a new subnuclear organelle called the nucleolar stress body (NoSB) in C. elegans, formed through the NOSR-1/NUMR-1 axis in response to nucleolar stress.

This study shows that inhibiting serine racemase with L-ABH prevents diabetic retinopathy by protecting retinal cells and maintaining glucose homeostasis in diabetic mice.

The paper identifies a U1 snRNP recognition motif that regulates chromatin retention of noncoding RNAs through experimental and computational methods.

The paper identifies mecciRNAs, circular RNAs from the mitochondrial genome that assist in the mitochondrial import of nuclear-encoded proteins by acting as molecular chaperones.