Author

Siem Yonas

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Assay:long-read sequencing· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anh-Thu Nguyen· 2 shared Chengde MaoiD· 2 shared Emile J. Batchelder-SchwabiD· 2 shared Hsin‐Chih YehiD· 2 shared Naseem Siraj· 2 shared Pengyu Y. ReniD· 2 shared S H Kim· 2 shared Y.-I. CheniD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Anh-Thu Nguyen

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Author profile →

2 papers

Recent·Most cited

Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform

Yu-An Kuo, Y.-I. Chen, Naseem Siraj, Yujie He, Zhenglin Yang, Yanxing Wang, Emile J. Batchelder-Schwab, Zeynep Korkmaz, Siem Yonas, Trung D. Nguyen, Soonwoo Hong, Anh-Thu Nguyen, S H Kim, Saeed Seifi, Po‐Hsun Fan, , Hsin‐Chih Yeh

This paper optimizes a DNA-based fluorogenic aptamer (D-FAP) using a screening-and-simulation pipeline on a repurposed sequencing platform, achieving improved fluorescence properties.

ACS Sensors · May 11, 2026Peer-reviewedBiophysics

Lifetime-based multiplexed detection of viral RNA using fluorogenic aptamers

Y R Chen, Yu-An Kuo, Yujie He, Naseem Siraj, Emile J. Batchelder-Schwab, Yin-Jui Chang, Siem Yonas, Yuting Wu, Zhenglin Yang, Anh-Thu Nguyen, S H Kim, Yi Lu, Chengde Mao, Pengyu Y. Ren, Hsin‐Chih Yeh

This paper introduces a fluorescence-lifetime-based multiplexed detection strategy using fluorogenic aptamers to distinguish viral RNA targets with minimal cross-reactivity and spectral overlap.

bioRxiv · Apr 15, 2026 · PreprintBioengineering