Yanxing Wang

A High-Throughput Platform for Rapid Adaptation of DNA Aptamers to SARS-CoV-2 Evolution

This paper develops a high-throughput platform to rapidly adapt DNA aptamers against evolving SARS-CoV-2 variants, identifying mutants with improved binding affinity and specificity.

Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform

This paper optimizes a DNA-based fluorogenic aptamer (D-FAP) using a screening-and-simulation pipeline on a repurposed sequencing platform, achieving improved fluorescence properties.

A machine-learning-guided hydrogen-bonded organic framework for long-term, ultrasound-triggered pain therapy

This paper develops a machine learning-guided hydrogen-bonded organic framework for ultrasound-triggered pain therapy, showing effective long-term analgesia in a rat model.