Author

Zhenglin Yang

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Zhenglin YangiD2 papers · University of Electronic Science and Technology of China
Zhenglin YangiD1 paper · University of Electronic Science and Technology of China

Biology Disciplines

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Bioengineering· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Anh-Thu Nguyen· 3 shared Hsin‐Chih YehiD· 3 shared Pengyu Y. ReniD· 3 shared Yi LuiD· 3 shared Yu-An Kuo· 3 shared Yujie HeiD· 3 shared Yuting WuiD· 3 shared Chengde MaoiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBioengineering

Anh-Thu Nguyen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A High-Throughput Platform for Rapid Adaptation of DNA Aptamers to SARS-CoV-2 Evolution

Yujie He, Zhenglin Yang, Yu-An Kuo, Yuting Wu, Diego Fonseca-Albert, Kyle K Le, Jeffrey Guo, Yanxing Wang, Anh-Thu Nguyen, Yuan‐I Chen, Sohyun Kim, Weiru Chen, Saeed Seifi, Soonwoo Hong, Trung Duc Nguyen, , Hsin‐Chih Yeh

This paper develops a high-throughput platform to rapidly adapt DNA aptamers against evolving SARS-CoV-2 variants, identifying mutants with improved binding affinity and specificity.

ACS Nano · Aug 14, 2026Peer-reviewedBioengineering

Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform

Yu-An Kuo, Y.-I. Chen, Naseem Siraj, Yujie He, Zhenglin Yang, Yanxing Wang, Emile J. Batchelder-Schwab, Zeynep Korkmaz, Siem Yonas, Trung D. Nguyen, Soonwoo Hong, Anh-Thu Nguyen, S H Kim, Saeed Seifi, Po‐Hsun Fan, , Hsin‐Chih Yeh

This paper optimizes a DNA-based fluorogenic aptamer (D-FAP) using a screening-and-simulation pipeline on a repurposed sequencing platform, achieving improved fluorescence properties.

ACS Sensors · May 11, 2026Peer-reviewedBiophysics

Lifetime-based multiplexed detection of viral RNA using fluorogenic aptamers

Y R Chen, Yu-An Kuo, Yujie He, Naseem Siraj, Emile J. Batchelder-Schwab, Yin-Jui Chang, Siem Yonas, Yuting Wu, Zhenglin Yang, Anh-Thu Nguyen, S H Kim, Yi Lu, Chengde Mao, Pengyu Y. Ren, Hsin‐Chih Yeh

This paper introduces a fluorescence-lifetime-based multiplexed detection strategy using fluorogenic aptamers to distinguish viral RNA targets with minimal cross-reactivity and spectral overlap.

bioRxiv · Apr 15, 2026 · PreprintBioengineering