Author

Simon Eckert

Freie Universität Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amir Amiri‐YektaiD· 1 shared Anne‐Pascale BouiniD· 1 shared Caroline CaziniD· 1 shared Charles CouttoniD· 1 shared Christophe ArnoultiD· 1 shared Corinne LoeuilletiD· 1 shared Elsa Giordani· 1 shared Emeline LambertiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Amir Amiri‐YektaORCID

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2 papers

Recent·Most cited

Structural basis for alternative 3' splice site selection in the human spliceosome active center

Gabriele Marcianò, Simon Eckert, Luiza Zuvanonv, Takero Miyagawa, Leo Yang, George Datcu, Yuewen Sheng, Hye Young Kwon, Louis Cameron, Florian Heyd, Sebastian M. Fica

The paper presents cryo-EM structures of human spliceosomes showing how SDE2, FAM32A, and Prp18 regulate 3' splice site selection by counteracting distal bias and stabilizing weaker proximal sites.

bioRxiv · Aug 6, 2026 · PreprintMolecular Biology

Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse

Jana Muroňová, Zine‐Eddine Kherraf, Elsa Giordani, Emeline Lambert, Simon Eckert, Caroline Cazin, Amir Amiri‐Yekta, Magali Court, Geneviève Chevalier, Guillaume Martinez, Yasmine Neirijnck, Françoise Kühne, Lydia Wehrli, Nikolai Klena, Virginie Hamel, , Christophe Arnoult

This study identifies bi-allelic CCDC146 mutations as a cause of non-syndromic male infertility in humans and mice, showing its role in sperm flagellum structure and microtubule organization.

bioRxiv · Feb 27, 2023 · PreprintGenetics