Author

Gabriele Marcianò

University of OxfordORCID 0000-0003-2720-652XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aleksandra Ciszek· 1 shared Bungo AkiyoshiiD· 1 shared Christina RedfieldiD· 1 shared Christopher W. WoodiD· 1 shared Florian HeydiD· 1 shared George Datcu· 1 shared Hye Young Kwon· 1 shared Leo Yang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Aleksandra Ciszek

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 18, 2026

The centromere localization domain of kinetoplastid kinetochore protein KKT2 recognizes the free N-terminus of histone H3

Aleksandra Ciszek, Patryk Ludzia, Gabriele Marcianò…·Bungo Akiyoshi

This study shows that the KKT2 CL domain binds histone H3 N-terminus and that methylation of this region disrupts binding, suggesting a mechanism for kinetochore assembly in kinetoplastids.

DOI 10.64898/2026.08.13.744621

proteomicsexperimental assay

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Molecular BiologybioRxivPreprintAug 6, 2026

Structural basis for alternative 3' splice site selection in the human spliceosome active center

Gabriele Marcianò, Simon Eckert, Luiza Zuvanonv…·Sebastian M. Fica

The paper presents cryo-EM structures of human spliceosomes showing how SDE2, FAM32A, and Prp18 regulate 3' splice site selection by counteracting distal bias and stabilizing weaker proximal sites.

DOI 10.64898/2026.08.05.741260

humanexperimental assay

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