Jessica Okosun

The paper shows that immune surveillance in germinal centers eliminates premalignant B-cells, but lymphoma-like mutations allow immune escape and progression to lymphoma.

This study identifies relapse-founding cancer persister cells in follicular lymphoma using a mouse model and shows their transcriptional program is conserved in humans, with potential therapeutic targets identified.

This study identifies mutations in the IgG heavy chain in follicular lymphoma and EZB DLBCL that enhance BCR signalling and oncogenicity by disrupting the IgG intracellular tail.

IBRAP is a tool that benchmarks scRNA-seq analysis pipelines by allowing interchangeable methods and metrics to find optimal combinations for different data types and studies.