Author

Sophia Lewis

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

April Rose FosteriD· 1 shared Aurélie CenieriD· 1 shared Camilla Salvestrini· 1 shared D. Leanne JonesiD· 1 shared Daniel R. ZerbinoiD· 1 shared Felicity PayneiD· 1 shared Francesca Marta Perrone· 1 shared Franco TorrenteiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

April Rose FosterORCID

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1 paper

Recent·Most cited

Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids

Rachel D. Edgar, Francesca Marta Perrone, April Rose Foster, Felicity Payne, Sophia Lewis, Komal Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert B. Heuschkel, Kai Oliver Hensel, Rebecca Harris, D. Leanne Jones, Daniel R. Zerbino, Matthias Zilbauer

This study shows that long-term culture of human intestinal organoids leads to DNA methylation changes, altered gene expression, and functional shifts, suggesting potential confounding effects in research.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2022Peer-reviewedGenomics