Author

Komal Nayak

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Matthias ZilbaueriD· 3 shared Aurélie CenieriD· 2 shared Andrew E. FirthiD· 1 shared April Rose FosteriD· 1 shared Ateequr RehmaniD· 1 shared Bernd Mußler· 1 shared Camilla Salvestrini· 1 shared D. Leanne JonesiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

Matthias ZilbauerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Flexibility and modulation of translation initiation in enterovirus genomes

Rhian L. O’Connor, Georgia M. Cook, Jacqueline Hankinson, Ksenia V. Fominykh, Samantha H. Cheng, Daniel A Nash, Aurélie Cenier, Komal Nayak, Stephen C. Graham, Janet Elwyn Deane, Matthias Zilbauer, Andrew E. Firth, Valeria Lulla

This study shows enteroviruses can use two upstream AUGs for translation initiation, with the second AUG providing a competitive advantage in specific host environments.

PLoS Pathogens · Feb 9, 2026Peer-reviewedMicrobiology

Human Milk Oligosaccharides Modulate Inflammatory Responses and Lipid Metabolism in a Human Intestinal Organoid Model

Ellie Slater, Jaesub Park, Thomas W. Dennison, Tim N. Mak, Igor Bendik, Ateequr Rehman, Bernd Mußler, Frank Wiens, Komal Nayak, Matthias Zilbauer

This study examines how a blend of human milk oligosaccharides affects intestinal epithelial cells in fetal and pediatric organoids, showing stage-specific responses and anti-inflammatory effects.

Clinical Nutrition · Dec 27, 2025Peer-reviewedCell Biology

Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids

Rachel D. Edgar, Francesca Marta Perrone, April Rose Foster, Felicity Payne, Sophia Lewis, Komal Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert B. Heuschkel, Kai Oliver Hensel, Rebecca Harris, D. Leanne Jones, Daniel R. Zerbino, Matthias Zilbauer

This study shows that long-term culture of human intestinal organoids leads to DNA methylation changes, altered gene expression, and functional shifts, suggesting potential confounding effects in research.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2022Peer-reviewedGenomics