Author

Sophia Xiao

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Amber Leila SarvestaniiD· 2 shared Andrew M. BlakelyiD· 2 shared Jason HoiD· 2 shared Jeremy L. DavisiD· 2 shared Jonathan Matthew HernandeziD· 2 shared Kenneth LubericeiD· 2 shared Kirsten RemmertiD· 2 shared Michael B. YaffeiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Amber Leila SarvestaniORCID

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2 papers

Recent·Most cited

Tumor-specific Kinase Motif Enrichment Analysis Identifies Personalized Therapeutic Cancer Targets

Tracey Pu, Brian A. Joughin, Priyanka Prakash Desai, Steven Donald Forsythe, Ronald J. Holewinski, Kirsten Remmert, Billel Gasmi, Kendra Coleman, Timothy Leach, Allan M. Johansen, Nicole Russell, Lichun Ma, Ashley J. Rainey, Amber Leila Sarvestani, Emily Smith, , Jonathan Matthew Hernandez

The paper uses phosphoproteomic data and KMEA to identify tumor-specific kinase activity in GEP-NETs, revealing potential therapeutic targets.

bioRxiv · Aug 9, 2026 · PreprintCancer Biology

A simple circuit to sustain intact tumor microenvironments for complex drug interrogations

Amber Leila Sarvestani, Samantha M. Ruff, Kirsten Remmert, Martha E. Teke, Emily A. Verbus, Areeba Saif, Marcial Garmendia‐Cedillos, Alex Rossi, Ashley Rainey, Krystle J. Nomie, Surajit Sinha, Michael M. Wach, Carrie Ryan, Stephanie N. Gregory, Priyanka Desai, , Jonathan Matthew Hernandez

The paper develops a perfusion circuit system to preserve tumor microenvironments in 3D patient-derived tumor models for up to 48 hours, enabling complex drug interrogations.

bioRxiv · Oct 26, 2025 · PreprintCancer Biology