Author

Jeremy L. Davis

National Institutes of HealthORCID 0000-0002-6334-6936Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:database / resource· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Amber Leila SarvestaniiD· 2 shared Andrew M. BlakelyiD· 2 shared Jason HoiD· 2 shared Jonathan Matthew HernandeziD· 2 shared Kenneth LubericeiD· 2 shared Kirsten RemmertiD· 2 shared Michael B. YaffeiD· 2 shared Sophia Xiao· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Amber Leila SarvestaniORCID

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Author profile →

4 papers

Recent·Most cited

Tumor-specific Kinase Motif Enrichment Analysis Identifies Personalized Therapeutic Cancer Targets

Tracey Pu, Brian A. Joughin, Priyanka Prakash Desai, Steven Donald Forsythe, Ronald J. Holewinski, Kirsten Remmert, Billel Gasmi, Kendra Coleman, Timothy Leach, Allan M. Johansen, Nicole Russell, Lichun Ma, Ashley J. Rainey, Amber Leila Sarvestani, Emily Smith, , Jonathan Matthew Hernandez

The paper uses phosphoproteomic data and KMEA to identify tumor-specific kinase activity in GEP-NETs, revealing potential therapeutic targets.

bioRxiv · Aug 9, 2026 · PreprintCancer Biology

UniST: A Unified Computational Framework for 3D Spatial Transcriptomics Reconstruction

Lan Shui, Yunhe Liu, Idania Carolina Lubo Julio, Jean Rene V. Clemenceau, Xen Ping Hoi, Yibo Dai, Wei Lü, Jimin Min, Khaja B. Khan, Bailey Roemer, Mei Jiang, Rebecca E. Waters, Karen Colbert, Anirban Maitra, Max Wintermark, , Ziyi Li

UniST reconstructs dense 3D spatial transcriptomics data from sparse serial sections, restoring structural continuity and biologically meaningful expression patterns in multiple tissue contexts.

bioRxiv · Mar 16, 2026 · PreprintBioinformatics

A simple circuit to sustain intact tumor microenvironments for complex drug interrogations

Amber Leila Sarvestani, Samantha M. Ruff, Kirsten Remmert, Martha E. Teke, Emily A. Verbus, Areeba Saif, Marcial Garmendia‐Cedillos, Alex Rossi, Ashley Rainey, Krystle J. Nomie, Surajit Sinha, Michael M. Wach, Carrie Ryan, Stephanie N. Gregory, Priyanka Desai, , Jonathan Matthew Hernandez

The paper develops a perfusion circuit system to preserve tumor microenvironments in 3D patient-derived tumor models for up to 48 hours, enabling complex drug interrogations.

bioRxiv · Oct 26, 2025 · PreprintCancer Biology

ClinGen CDH1 specifications for the ACMG/AMP guidelines: improvement of germline variant clinical assertions and updated curation guidelines

Xi Luo, Jamie L. Maciaszek, Bryony A. Thompson, Huei San Leong, Katherine Dixon, Sónia Sousa, Michael Anderson, Maegan E. Roberts, Kristy Lee, Amanda B. Spurdle, Arjen R. Mensenkamp, Terra Brannan, Carolina Pardo, Liying Zhang, Tina F. Pesaran, , Rachid Karam

The paper updates CDH1 variant curation guidelines to resolve conflicting interpretations and reduce variants of uncertain significance for clinical use.

medRxiv · Nov 1, 2021 · PreprintGenetic & Genomic Medicine