Author

Surajit Sinha

National Institutes of HealthORCID 0000-0002-7204-2248Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Jonathan Matthew HernandeziD· 3 shared Abir Kumar PandaiD· 2 shared Amber Leila SarvestaniiD· 2 shared Andrew M. BlakelyiD· 2 shared Ethan M. ShevachiD· 2 shared Jason HoiD· 2 shared Jeremy L. DavisiD· 2 shared Kenneth LubericeiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Jonathan Matthew HernandezORCID

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3 papers

Recent·Most cited

Tumor-specific Kinase Motif Enrichment Analysis Identifies Personalized Therapeutic Cancer Targets

Tracey Pu, Brian A. Joughin, Priyanka Prakash Desai, Steven Donald Forsythe, Ronald J. Holewinski, Kirsten Remmert, Billel Gasmi, Kendra Coleman, Timothy Leach, Allan M. Johansen, Nicole Russell, Lichun Ma, Ashley J. Rainey, Amber Leila Sarvestani, Emily Smith, , Jonathan Matthew Hernandez

The paper uses phosphoproteomic data and KMEA to identify tumor-specific kinase activity in GEP-NETs, revealing potential therapeutic targets.

bioRxiv · Aug 9, 2026 · PreprintCancer Biology

Antibody Blockade of Ly49/MHC-I interactions enhances Innate and Adaptive Immunity Against Cancer Metastasis

Abir Kumar Panda, Surajit Sinha, Kannan Natarajan, Jiansheng Jiang, Sruthi Chempati, Soha Kazmi, Yong-hee Kim, Suveena Sharma, Paul Schaughency, Lisa F. Boyd, Jonathan Matthew Hernandez, David H. Margulies, Ethan M. Shevach

This study shows that the anti-MHC-I antibody M1/42 enhances anti-tumor immunity by activating NK and adaptive immune cells, reducing metastasis in mouse models of cancer.

bioRxiv · May 12, 2026 · PreprintCancer Biology

A simple circuit to sustain intact tumor microenvironments for complex drug interrogations

Amber Leila Sarvestani, Samantha M. Ruff, Kirsten Remmert, Martha E. Teke, Emily A. Verbus, Areeba Saif, Marcial Garmendia‐Cedillos, Alex Rossi, Ashley Rainey, Krystle J. Nomie, Surajit Sinha, Michael M. Wach, Carrie Ryan, Stephanie N. Gregory, Priyanka Desai, , Jonathan Matthew Hernandez

The paper develops a perfusion circuit system to preserve tumor microenvironments in 3D patient-derived tumor models for up to 48 hours, enabling complex drug interrogations.

bioRxiv · Oct 26, 2025 · PreprintCancer Biology