Author

Sophia Y. Breusegem

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Aaran VijayakumaraniD· 1 shared Adrián Fragoso-LunaiD· 1 shared Ajeian Jila· 1 shared Analle Abuammar· 1 shared Andrew J. MurrayiD· 1 shared Anne F. J. JansseniD· 1 shared Christian G. RiedeliD· 1 shared Christopher GodbehereiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Aaran VijayakumaranORCID

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2 papers

Recent·Most cited

Cell BiologyCell ReportsPeer-reviewedJul 1, 2026

3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication

Aaran Vijayakumaran, Christopher Godbehere, Analle Abuammar…·Vito Mennella

This study reveals a communication axis between motile cilia, rootlets, and mitochondria in respiratory epithelium, enhancing ciliary motility and ATP production.

2 citationstop 5%

humanspatial transcriptomics

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedFeb 16, 2025

A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein translation

Sophia Y. Breusegem, Jack W. Houghton, Raquel Romero-Bueno…·Delphine Larrieu

A whole genome multiparametric CRISPR screen in progeria identifies new pathways that can reverse cellular aging phenotypes by targeting protein translation and related processes.

4 citations

humanCRISPR screen

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