Single Cell Integration Characterises Metaplasia in Inflammatory Intestinal Diseases
Amanda J. Oliver, Ni Huang, Ruoyan Li, Raquel Bartolomé-Casado, Hogne Røed Nilsen, Victòria Gudiño, Elisa Melón-Ardanaz, Michael E. B. FitzPatrick, Nicholas M. Provine, Krzysztof Polański, Simon Koplev, Lisa Marie Milchsack, Emma Dann, Alexander V. Predeus, Batuhan Çakır, , Sarah Amalia Teichmann
The paper integrates single-cell RNA-seq datasets across the GI tract to identify epithelial metaplasia in inflammatory diseases, showing its role in inflammation through immune cell interactions.
bioRxiv · Oct 11, 2024 · PreprintGenomics