Activation of vitamin D signaling suppresses platinum-induced ovarian cancer stem cell plasticity
Tara X. Metcalfe, Sophie Xanders, Renee A. Kinne, Saranya Rajendran, Shu Zhang, Peter C. Hollenhorst, Alexandre Gaspar‐Maia, Heather M. O’Hagan, Kenneth P. Nephew
This study shows that vitamin D signaling activation suppresses platinum-induced ovarian cancer stem cell plasticity, reducing stemness and tumor growth in vivo.
bioRxiv · Sep 23, 2026 · PreprintCancer Biology