Author

Peter C. Hollenhorst

Indiana University BloomingtonORCID 0000-0002-1995-0028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Renee A. Kinne· 2 shared Alexandre Gaspar‐MaiaiD· 1 shared Heather M. O’HaganiD· 1 shared Kenneth P. NephewiD· 1 shared Saranya RajendraniD· 1 shared Shu ZhangiD· 1 shared Sophie Xanders· 1 shared Tara X. MetcalfeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

Renee A. Kinne

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2 papers

Recent·Most cited

Oncogenic ETS factors expressed from fusion genes utilize EWSR1 to associate with the paraspeckle and regulate transcription.

Renee A. Kinne, Peter C. Hollenhorst

This study shows that EWSR1 from fusion genes interacts with paraspeckles to regulate transcription in cancers, and disrupting paraspeckles mimics loss of oncogenic ETS factors.

bioRxiv · Oct 14, 2026 · PreprintCancer Biology

Activation of vitamin D signaling suppresses platinum-induced ovarian cancer stem cell plasticity

Tara X. Metcalfe, Sophie Xanders, Renee A. Kinne, Saranya Rajendran, Shu Zhang, Peter C. Hollenhorst, Alexandre Gaspar‐Maia, Heather M. O’Hagan, Kenneth P. Nephew

This study shows that vitamin D signaling activation suppresses platinum-induced ovarian cancer stem cell plasticity, reducing stemness and tumor growth in vivo.

bioRxiv · Sep 23, 2026 · PreprintCancer Biology