Author

Susan Irtenkauf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ana C. deCarvalhoiD· 1 shared Artem BerezovskyiD· 1 shared Claudius MuelleriD· 1 shared Douglas RudeniD· 1 shared Emanuel F. PetricoiniD· 1 shared Houtan NoushmehriD· 1 shared Indrani Datta· 1 shared Katherine GurdzieliD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ana C. deCarvalhoORCID

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1 paper

Recent·Most cited

Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells

Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F. Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, , Ana C. deCarvalho

This study examines how genomic background and developmental state affect signaling pathways and therapy response in GBM patient-derived cells, finding that differentiation increases TMZ resistance and activates DNA-damage interferon responses.

bioRxiv · Mar 14, 2024 · PreprintCancer Biology