Author

Stephen Brown

University College LondonPrimary ORCID profile (0000-0002-7581-7491 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Stephen BrowniD1 paper · University of Sheffield

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A FortoniD· 1 shared Adedeji Daniel OgunyemiiD· 1 shared Ahana Dutta· 1 shared Alexis L. RohouiD· 1 shared Ana C. deCarvalhoiD· 1 shared Andreas F. R. HühmeriD· 1 shared Artem BerezovskyiD· 1 shared Brittany Nortman· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A FortonORCID

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3 papers

Recent·Most cited

Large-scale single-molecule analysis of tau proteoforms

James H. Joly, Vivekananda Budamagunta, Zhengjian Zhang, Brittany Nortman, Maryam Jouzi, Rajat Bhatnagar, Jarrett D. Egertson, Michael E. Flaster, Rob Grothe, Sanjib K Guha, Kota Kaneshige, Kevin McVey, Nicholas Nelson, Rukshan T. Perera, Steven J. Tan, , Cara Li

This paper introduces IMaP, a method to analyze tau proteoforms at the single-molecule level, revealing ordered phosphorylation patterns and disease-specific modifications.

Nature Methods · Sep 1, 2026Peer-reviewedBiochemistry

Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells

Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F. Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, , Ana C. deCarvalho

This study examines how genomic background and developmental state affect signaling pathways and therapy response in GBM patient-derived cells, finding that differentiation increases TMZ resistance and activates DNA-damage interferon responses.

bioRxiv · Mar 14, 2024 · PreprintCancer Biology

Reorganization of the neurobiology of language after sentence overlearning

Jeremy I Skipper, Sarah Aliko, Stephen Brown, Yoon Ju Jo, Serena Lo, Emilia Molimpakis, Daniel Robert Lametti

The paper shows that overlearning sentences reorganizes brain networks for speech perception, shifting activity to sensorimotor regions and reducing reliance on traditional language regions.

Cerebral Cortex · Sep 8, 2021Peer-reviewedNeuroscience