Author

Swetha Gopalakrishnan

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Clémentine HallieziD· 1 shared Decio Laks EizirikiD· 1 shared Diego BalboaiD· 1 shared Églantine HeudeiD· 1 shared Federica VecchioiD· 1 shared Francesca PalaiD· 1 shared Francina Langa VivesiD· 1 shared Gabrielle KardoniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Clémentine HalliezORCID

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2 papers

Recent·Most cited

The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α

Vikash Chandra, Hazem Ibrahim, Clémentine Halliez, Rashmi B. Prasad, Federica Vecchio, Om Prakash Dwivedi, Jouni Kvist, Diego Balboa, Jonna Saarimäki‐Vire, Hossam Montaser, Tom Barsby, Väinö Lithovius, Isabella Artner, Swetha Gopalakrishnan, Leif Groop, , Timo Otonkoski

This study shows that TYK2 is critical for β-cell development by regulating KRAS and IFN responses, suggesting TYK2 inhibition as a therapeutic target for type 1 diabetes.

Nature Communications · Oct 26, 2022Peer-reviewedMolecular Biology

A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle

Glenda Comai, Églantine Heude, Sébastian Mella, Sylvain Paisant, Francesca Pala, Mirialys Gallardo, Francina Langa Vives, Gabrielle Kardon, Swetha Gopalakrishnan, Shahragim Tajbakhsh

The paper identifies a genetic hierarchy involving Tbx1, Isl1, and Met/HGF signaling that regulates antero-posterior patterning of esophagus striated muscle in mice.

eLife · Sep 18, 2019Peer-reviewedDevelopmental Biology