Author

T. A. Reese

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 6 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G. Wang· 4 shared A. Lowe· 3 shared L. Tao· 3 shared T. Chang· 3 shared C. Zarek· 2 shared I. Dozmorov· 2 shared P. Dryden· 2 shared B. Levine· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

G. Wang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Norovirus MLKL-like pore forming protein initiates programed cell death for viral egress

G. Wang, D. Zhang, R. Orchard, D. A. Hancks, T. A. Reese

This study identifies a mechanism by which norovirus induces cell death and egress through an MLKL-like pore-forming protein that targets mitochondria.

bioRxiv · Mar 17, 2023Microbiology

Coinfection with Intestinal Parasite Expands Resident Macrophages and Impairs Control of Chronic Herpesvirus Infection

C. Zarek, C. Dende, J. Coronado, M. Pendse, P. Dryden, L. V. Hooper, T. A. Reese

This study shows that intestinal parasite infection expands resident macrophages via retinoic acid signaling, leading to increased herpesvirus infection and reactivation.

bioRxiv · Oct 5, 2022 · PreprintImmunology

CDKL5 regulates p62-mediated selective autophagy and host antiviral defense

J. W. Thinwa, Z. Zou, E. Parks, S. Sebti, K. Hui, V. Singh, Y. Wei, G. Urquhart, J. L. Jewell, J. K. Pfeiffer, B. Levine, T. A. Reese, M. U. Shiloh

This study identifies CDKL5 as a regulator of virophagy, showing it promotes p62-mediated autophagy of viral capsids and enhances antiviral defense.

bioRxiv · Sep 20, 2022Microbiology

WY14643 Increases Herpesvirus Replication Independent of PPARα Expression and Inhibits IFNβ Production

L. Tao, P. Dryden, A. Lowe, G. Wang, I. Dozmorov, T. Chang, T. A. Reese

This study shows that PPAR agonists like WY14643 increase herpesvirus replication and inhibit IFNβ production, independent of PPARα expression.

bioRxiv · Oct 29, 2021Immunology

Th2 Cytokine Modulates Herpesvirus Reactivation in a Cell Type Specific Manner

G. Wang, C. Zarek, T. Chang, L. Tao, A. Lowe, T. A. Reese

This study shows that IL-4 induces MHV68 reactivation in macrophages but not B cells, indicating cell-type specific regulation of herpesvirus reactivation.

bioRxiv · Sep 30, 2020Microbiology

Metabolic Control of Viral Infection through PPAR-α Regulation of STING Signaling

L. Tao, A. Lowe, G. Wang, I. Dozmorov, T. Chang, N. Yan, T. A. Reese

This study shows that PPAR-α activation increases herpesvirus replication, suppresses type I interferon, and inhibits STING signaling through ROS.

bioRxiv · Sep 13, 2019 · PreprintImmunology