Author

T. Barr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. Yu· 2 shared J. Zhang· 2 shared L.-S. Wang· 2 shared A. Jones· 1 shared A. Li· 1 shared A. Melcher· 1 shared B. M. Barker· 1 shared C. Ralph· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

J. Yu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enhancing oncolytic virotherapy by exosome-mediated microRNA reprograming of the tumour microenvironment.

V. Jennings, R. Rumbold-Hall, G. Migneco, T. Barr, K. Reilly, N. Ingram, I. St Hilare, S. Heaton, N. Alzamel, D. Jackson, C. Ralph, I. McNeish, J. C. Bell, A. Melcher, C. S. Ilkow, , F. Errington-Mais

This study uses oncolytic viruses to deliver miRNA to TAMs, reversing their immunosuppressive activity and improving ovarian cancer immunotherapy efficacy.

bioRxiv · Jun 7, 2024 · PreprintCancer Biology

The K18-hACE2 Transgenic Mouse Model Recapitulates Non-Severe and Severe COVID-19 in Response to Infectious Dose of SARS-CoV-2 Virus

J. Yu, W. Dong, A. Li, J. Zhang, M. Caligiuri, S. Jaramillo, H. L. Mead, N. E. Stone, A. Jones, D. R. Kollath, V. K. Coyne, M. Yearsley, L.-S. Wang, B. M. Barker, P. Keim, T. Barr

The paper characterizes the K18-hACE2 mouse model's response to different SARS-CoV-2 doses, showing dose-dependent disease severity and recovery, and compares it to human COVID-19 pathology.

bioRxiv · May 8, 2021Microbiology

The RNA m6A reader YTHDF2 controls NK cell anti-tumor and anti-viral immunity

S. Ma, J. Yan, T. Barr, J. Zhang, Z. Chen, L.-S. Wang, J. C. Sun, J. Chen, M. A. Caligiuri, J. Yu

This study shows YTHDF2, an m6A reader, enhances NK cell anti-tumor and anti-viral responses by regulating homeostasis, maturation, and effector function through STAT5 feedback and Tardbp interactions.

bioRxiv · Apr 26, 2021Immunology