Author

T. Bian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

C. Xing· 2 shared Y. Wang· 2 shared A. Bruijnzeel· 1 shared A. C. Lynch· 1 shared A. Fagan· 1 shared A. Scala· 1 shared A. Zingone· 1 shared B. Freeman· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. Xing

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

AB-free kava enhances resilience against the adverse health effects of tobacco smoke in mice

T. Bian, A. C. Lynch, K. Ballas, J. Mamallapalli, B. Freeman, A. Scala, Y. Wang, H. Trabouls, R. k. Chellian, A. Fagan, Z. Tang, H. Ding, U. De, K. M. Fredenburg, Z. Huo, , C. Xing

This study evaluates AB-free kava's effects on tobacco smoke-exposed mice, showing it mitigates health deficits with safety, suggesting potential for reducing tobacco-related harm.

bioRxiv · Jun 25, 2024 · PreprintPharmacology & Toxicology

Structural Insights into Branch Site Proofreading by Human Spliceosome

X. Zhang, X. Zhan, T. Bian, F. Yang, P. Li, Y. Lu, Z. Xing, Q. Cliff Zhang, Y. Shi

The paper reports atomic structures of human spliceosome complexes to elucidate PRP5's role in branch site proofreading during pre-mRNA splicing.

bioRxiv · Nov 7, 2022Biochemistry

NNAL, a major metabolite of tobacco-specific carcinogen NNK, promotes lung cancer progression through deactivating LKB1 in an isomer-dependent manner

T. Bian, Y. Wang, J. F. Botello, Q. Hu, Y. Jiang, A. Zingone, P. A. Corral, F. Z. Aly, Y. Wu, B. M. Ryan, L. Jin, C. Xing

This study shows that (R)-NNAL promotes lung cancer progression by deactivating LKB1 through β-AR signaling, while (S)-NNAL has weaker effects.

bioRxiv · Jun 15, 2021 · PreprintCancer Biology