Author

Z. Huo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 4 Organism:human· 3 Assay:metabolomics· 2 Organism:mouse· 2

Frequent Co-Authors

K. A. Esser· 3 shared J. Wang· 2 shared X. Zhang· 2 shared A. Altintas· 1 shared A. Krook· 1 shared A. Linde Basse· 1 shared A. Prabhat· 1 shared A. Waddell· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersPhysiology

K. A. Esser

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

New role of cardiomyocyte Bmal1 in the regulation of sex-specific heart transcriptomes

X. Zhang, S. B. Procopio, H. Ding, M. G. Semel, E. A. Schroder, T. S. Seward, P. Du, K. K. Wu, S. R. Johnson, A. Prabhat, D. J. Schneider, I. G. Stumpf, E. R. Rozmus, Z. Huo, B. P. Delisle, K. A. Esser

This study shows that cardiomyocyte Bmal1 is essential for sex-specific gene expression in the adult mouse heart, as its loss reduces sex differences in circadian transcriptomes.

bioRxiv · Apr 18, 2024 · PreprintPhysiology

Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer

Z. Huo, Y. Duan, D. Zhan, X. Xu, N. Zheng, J. Cai, R. Sun, J. Wang, F. Cheng, Z. Gao, C. Xu, W. Liu, Y. Dong, S. Ma, Q. Zhang, , Y. Wang

This study uses proteomic profiling to stratify small cell lung cancer into three subtypes with distinct clinical outcomes and treatment responses, identifying potential therapeutic targets and improving prognosis prediction.

bioRxiv · Oct 22, 2023 · PreprintCancer Biology

Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training.

M. R. Viggars, H. E. Berko, S. J. Hesketh, C. A. Wolff, M. A. Gutierrez Monreal, R. A. Martin, I. G. Jennings, Z. Huo, K. A. Esser

This study shows that BMAL1 in skeletal muscle is essential for transcriptional responses to exercise and peripheral tissue adaptations, with its loss leading to divergent transcriptomic and metabolomic changes and increased inflammation.

bioRxiv · Oct 13, 2023Physiology

Disrupted circadian core-clock oscillations in Type 2 Diabetes are linked to altered rhythmic mitochondrial metabolism

B. M. Gabriel, A. Altintas, J. A. B. Smith, L. Sardon Puig, X. Zhang, A. Linde Basse, R. C. Laker, H. Gao, Z. Liu, L. Dollet, J. T. Treebak, A. Zorzano, Z. Huo, M. Ryden, J. T. Lanner, , J. R. Zierath

bioRxiv · Feb 24, 2021Physiology

The DAXX-SREBP axis promotes oncogenic lipogenesis and tumorigenesis

I. Mahmud, G. Tian, J. Wang, J. Lewis, A. Waddell, M. L. Lydon, L. Y. Zhao, J.-L. Li, H. T. Purayil, Z. Huo, Y. Daaka, T. J. Garrett, D. Liao

This study identifies the DAXX-SREBP axis as a driver of lipogenesis and tumorigenesis by showing its role in activating lipogenic gene expression and promoting tumor growth.

bioRxiv · Dec 31, 2020 · PreprintCancer Biology