T. Dau

IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport

The paper shows that IER3IP1 mutations cause microcephaly by blocking ER-Golgi transport, leading to neuronal migration defects and ER distension.

Automated workflow for BioID improves reproducibility and identification of protein-protein interactions

The paper introduces an automated workflow for BioID to improve reproducibility and identification of protein-protein interactions by increasing throughput and reducing sample input requirements.

ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

This study develops a method to quantify proteasome interactomes and substrates in vivo using biotin ligases and a new mouse model, identifying novel interactors and substrates.

Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin

The paper evaluates protease alternatives to trypsin for protein identification in S. pombe, showing that sequential digestion with trypsin improves identification rates for several proteases.

An integrated workflow for cross-linking/mass spectrometry

The paper introduces a workflow combining sequential digestion and Xi software to improve cross-linking mass spectrometry detection of protein interactions.

Sequential digestion with Trypsin and Elastase in cross-linking/mass spectrometry

The paper introduces a sequential digestion method using trypsin and elastase to improve cross-linking/mass spectrometry analysis of protein complexes by accessing previously inaccessible regions.