Author

T. F. Pack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2

Frequent Co-Authors

A. Inoue· 2 shared I. Choi· 2 shared J. S. Smith· 2 shared S. Rajagopal· 2 shared A. W. Kahsai· 1 shared A. Warman· 1 shared C. Lee· 1 shared D. P. Staus· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

A. Inoue

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2 papers

Recent·Most cited

Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi:β-arrestin complexes

K. Z. Zheng, J. S. Smith, A. Warman, I. Choi, J. Gundry, T. F. Pack, A. Inoue, M. Caron, S. Rajagopal

The paper shows that biased agonists of CXCR3 differentially drive the formation of Gi:β-arrestin complexes, independent of G protein signaling or β-arrestin recruitment.

bioRxiv · Jun 11, 2020 · PreprintBiochemistry

Noncanonical scaffolding of Gαi and β-arrestin by G protein-coupled receptors

J. S. Smith, T. F. Pack, A. Inoue, C. Lee, X. Xiong, K. Zheng, A. W. Kahsai, I. Choi, Z. Ma, I. M. Levitan, L. K. Rochelle, D. P. Staus, J. C. Snyder, M. G. Caron, S. Rajagopal

The paper demonstrates that Gαi proteins can form complexes with β-arrestin, independent of their canonical G protein coupling, and these complexes can bind GPCRs and ERK.

bioRxiv · May 7, 2019Cell Biology