Author

T. J. Dalebout

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Assay:protein structure· 1 Organism:rat· 1 Research Focus:variant calling· 1

Frequent Co-Authors

E. J. Snijder· 4 shared M. Kikkert· 4 shared D. H. Barouch· 3 shared F. Wegmann· 3 shared H. Schuitemaker· 3 shared J. E. M. van der Lubbe· 3 shared R. C. Zahn· 3 shared S. K. Myeni· 3 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersImmunology

E. J. Snijder

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 8, 2021

Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection after sub-optimal vaccine dosing

J. E. M. van der Lubbe, S. K. Rosendahl Huber, A. Vijayan…·F. Wegmann

This study shows that a single dose of Ad26.COV2.S vaccine protects Syrian hamsters from G614 SARS-CoV-2 infection and prevents VAERD even with suboptimal immunity.

DOI 10.1101/2021.01.08.425915

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivNov 17, 2020

Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques

L. Solforosi, H. Kuipers, S. K. Rosendahl Huber…·R. C. Zahn

This study evaluates one- and two-dose regimens of the Ad26.COV2.S vaccine in rhesus macaques, showing higher antibody responses with two doses and protection against SARS-CoV-2 in aged animals.

DOI 10.1084/jem.20202756

ratexperimental assay

𝕏 PostBluesky

ImmunologybioRxivJul 30, 2020

Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

R. Bos, L. Rutten, J. E. M. van der Lubbe…·H. Schuitemaker

This paper evaluates a prefusion-stabilized SARS-CoV-2 Spike protein vaccine candidate, Ad26.COV2.S, showing potent neutralizing and Th1-polarized immune responses in mice.

DOI 10.1038/s41541-020-00243-x

mouseprotein structure

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 29, 2019

The deubiquitinating activity of Middle East respiratory syndrome coronavirus papain-like protease delays the innate immune response and enhances virulence in a mouse model

R. Knaap, R. Fernandez-Delgado, T. J. Dalebout…·M. Kikkert

This study shows that disrupting the deubiquitinating activity of MERS-CoV PLpro enhances innate immune responses and reduces virulence in mice.

DOI 10.1101/751578

mouseexperimental assay

𝕏 PostBluesky